Figure 2 | Scientific Reports

Figure 2

From: Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses

Figure 2

Protective capacity of antigen combinations against sporozoite challenge. Mice were immunized, challenged and protection assessed as described in the legend to Fig. 1. (A) liver-stage parasite burden. (B) pRBC FCAB. Com1/4 = PY01533 + PY03832; Com2/3 = PY01606 + PY03673; Com1/2/3/4 = PY01533 + PY03832 + PY01606 + PY03673. Data are presented as a scatter plot, with the line representing the mean and the error bars representing standard deviation (SD). Statistical comparison of immunised versus non-immunised infectivity controls was performed using one-way ANOVA followed by Bonferroni’s posthoc test, ****p < 0.0001, *** p < 0.001, **p < 0.01, *p < 0.05. The dotted line represents the mean value for infected but non-immunised control mice used to normalise vaccinated groups and for statistical analysis.

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