Table 1 Clinical characteristics of the hemodialysis patients and comparisons between those with and without type 2 diabetes mellitus (DM).

From: Xanthine oxidoreductase activity is associated with serum uric acid and glycemic control in hemodialysis patients

 

All patients

Patients without type 2 DM

Patients with type 2 DM

p

Age (years)

67.3 ± 10.9

67.9 ± 11.1

66.8 ± 10.5

0.600

Gender (male/female)

163 (89/74)

89 (45/44)

74 (44/30)

0.256

Body mass index (kg/m2)

21.3 ± 3.95

20.9 ± 3.96

21.8 ± 3.96

0.07

Systolic blood pressure (mmHg)

149.4 ± 26.4

147.5 ± 24.7

151.7 ± 28.5

0.245

Diastolic blood pressure (mmHg)

75.3 ± 13.0

74.2 ± 9.27

76.7 ± 16.4

0.11

Dialysis duration (months)

100 ± 87

129 ± 100

66 ± 53

<0.001

Plasma glucose (mg/dL)

114 ± 44

97 ± 21

128 ± 43

<0.001

Glycated albumin (%)

20.1 ± 4.73

Diabetes duration (years)

22.9 ± 12.8

Urea nitrogen (mg/dL)

65 ± 16

66 ± 16

64 ± 16

0.381

Creatinine (mg/dL)

9.9 ± 2.4

10.3 ± 2.6

9.4 ± 2.1

0.021

Serum albumin (g/dL)

3.2 ± 0.3

3.2 ± 0.3

3.2 ± 0.3

0.859

Alanine transaminase (IU/L)

11 ± 7

11 ± 7

11 ± 7

0.932

Uric acid (mg/dL)

7.3 ± 1.5

7.4 ± 1.4

7.2 ± 1.5

0.184

Hemoglobin (g/dL)

10.5 ± 1.2

10.6 ± 1.3

10.4 ± 1.0

0.209

Hs-CRP (mg/dL)

0.15 ± 0.27

0.12 ± 0.12

0.19 ± 0.40

0.255

Corrected calcium (mg/dL)

9.5 ± 0.8

9.4 ± 0.8

9.5 ± 0.7

0.881

Phosphate (mg/dL)

5.4 ± 1.3

5.5 ± 1.3

5.4 ± 1.3

0.957

Alkaline phosphatase (IU/L)

278 ± 145

266 ± 143

285 ± 138

0.521

Intact-PTH (pg/mL)

168 ± 132

169 ± 133

169 ± 133

0.954

XOR§ (pmol/h/mL)

21.4 ± 13.5

19.8 ± 12.4

23.4 ± 14.6

0.032

  1. Hs-CRP: high-sensitivity C-reactive protein, PTH: parathyroid hormone, §XOR: xanthine oxidoreductase.
  2. Glycated albumin was only measured in hemodialysis patients with type 2 DM (n = 74).
  3. *p < 0.05.
  4. Data are expressed as the mean ± SD. Unpaired Student’s t-test was used for comparisons of continuous variables that exhibited a normal distribution. Mann-Whitney U test was used for comparisons of continuous variables with a skewed distribution. Chi-square test was used for comparisons of categorical variables.