Figure 2

Significant clusters and t-statistic images for linear trends of intra-network functional connectivity among the emotional age groups (A) as well as the chronological age groups (B). Bar graphs represent the mean intra-network functional connectivity of significant clusters in each group. Error bars indicate 95% confidence intervals. A linear trend of decreased intra-network functional connectivity among the E-young, E-intermediate, and E-old groups was observed in the visual and sensorimotor networks at TFCE-corrected P < 0.05. In contrast, intra-network functional connectivity of the ECN increased linearly among the E-young, E-intermediate, and E-old groups. Among the chronological age groups, a significant decreasing trend in intra-network functional connectivity that is chronological age-dependent was found in the visual, sensorimotor, and salience networks. Detailed information on significant clusters is presented in Supplementary Figure 2, Supplementary Tables 1 and 2. Using BrainNet viewer⁴¹, three-dimensional rendering of RSNs was generated in the brain of standard space. Abbreviations: ECN, executive control network; TFCE, threshold-free cluster enhancement; RSN, resting state network; E-Y, emotionally young group; E-I, emotionally intermediate-age group; E-O, emotionally old group; C-Y, chronologically young group; C-I, chronologically intermediate-age group; C-O, chronologically old group.