Figure 2
From: Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori
GACC distribution on H. pylori P12 genome. (a) Forward strand (1340 GACC sites) and reverse strand (1240 GACC sites) of the P12 genome. From outside track: turquoise-ORFs; GACC frequency, orange–high, green–low; %GC content, pink–high, purple–low. Red bars denote areas of interest in the P12 genome (clockwise): comB, including type IV secretion system (TFSS) 2; PZ1–plasticity zone 1, including TFSS4; cagPAI–cag PAI pathogenicity island, including TFSS1; PZ2–plasticity zone 2; PZ3–plasticity zone 3, including TFSS3. (b) Distribution of the number of GACC sites in 500 bp region upstream of all P12 genes. (c) Distribution of the number of GACC sites in all P12 genes. (d) There was a significant positive correlation between the number of GACC sites within a gene and the length of the gene (Spearman’s correlation).
