Figure 6 | Scientific Reports

Figure 6

From: Overexpression of DYRK1A, a Down Syndrome Candidate gene, Impairs Primordial Germ Cells Maintenance and Migration in zebrafish

Figure 6

Verification of aberrant expression of PGCs key factors in DYRK1A overexpressed embryos. Analysis of localization and strength of ca15b and piwil1 in DYRK1A overexpressed embryos by WISH. All of embryos are 50%-epiboly stage with top view. Arrows show the normal location of detected gene, arrowheads demonstrate the aberrant position induced by overexpressed DYRK1A. Histogram representing the relative expression of ca15b and piwil1 in GFP injected and DYRK1A overexpressed embryos detected by qPCR.

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