Figure 2 | Scientific Reports

Figure 2

From: Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats

Figure 2

Experimental design and treatment strategy of midgut volvolus. (A) Experimental design. Rats were subjected to 360° volvulus for <1 min (Sham; N = 4) or 3 hours. Rats received inactivated DNase1 (Control; N = 8), active DNase1 (DNase1, N = 8), or a combination of LMWH and tPA (LMWH/tPA, N = 8) immediately after detorsion of the intestine. (B) Survival of the rats after volvulus or sham and treatment. Three rats in the control group and one rat in the LMWH/tPA group did not survive volvulus.

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