Figure 2
eRNAs in many cell types. (A) The saturation curves of eRNA regions obtained by Weibull fitting. Mean eRNA region count (blue line) and mean genome coverage (green line) for x cell types after clustering from 20,000 random samples (solid line) were fit using the Weibull distribution (corresponding dashed line). The elements are non-overlapping and have a maximum length of 5,000 bp. (B) Cell specificity of eRNA regions (red) and weakly-transcribed enhancers (blue) regions and their associated genes displayed as a violin plot. Medians are marked with green crosses. (C) Gene Ontology terms for eRNA-associated genes in 14 human cell/tissue types with corresponding P-values. (D) Heatmap showing the correlations between the expression levels of eRNAs and their associated genes across 14 human cell/tissue types. Colour scale reflects the density of Spearman correlation coefficients.
