Figure 6 | Scientific Reports

Figure 6

From: Temporal expression pattern of genes during the period of sex differentiation in human embryonic gonads

Figure 6

Immunohistochemical detection of prominent markers in human embryonic and fetal testis aged 48–64 days pc (week 6–9 pc). GAGE and LIN28 were detected in germ cells. AMH and SOX9 were detected in Sertoli cells. CYP17A1 was detected in Leydig cells from day 54 pc. WNT2B was detected in Sertoli cells in week 6–7 changing to Leydig cells in week 8–9. GLI1 was detected in testicular germ cells, Sertoli and Leydig cells. ETV5 showed a relatively low general expression in testis, with germ cells staining more intense than somatic cells. G = germ cell; S = Sertoli cells, L = Leydig cells; so = somatic cells.

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