Table 1 Apparent Ca2+ affinity and Hill slope of Cx46 at different voltages. Data presented as mean ± SEM. N; number of inhibition curves.
From: Calcium binding and voltage gating in Cx46 hemichannels
Voltage | −50 mV | −30 mV | −20 mV | 0 mV | 10 mV | 20 mV |
|---|---|---|---|---|---|---|
Log IC50 | −1.09 ± 0.06 | −1.1 ± 0.1 | −1.09 ± 0.06 | −0.8 ± 0.1 | −0.5 ± 0.1 | −0.2 ± 0.1 |
Hill slope | −1.9 ± 0.2 | −2.5 ± 0.7 | 2.4 ± 0.2 | −2.0 ± 0.2 | −2.3 ± 0.2 | −2.0 ± 0.6 |
N | 6 | 6 | 4 | 5 | 3 | 3 |
