Figure 4 | Scientific Reports

Figure 4

From: Inhibition of myeloid differentiation primary response protein 88 provides neuroprotection in early brain injury following experimental subarachnoid hemorrhage

Figure 4

Effect of MyD88 inhibition on the expression of activated JNK, ERK, p38, and c-Jun at 24 h post SAH. Western blots show JNK, p-JNK (a), ERK, p-ERK1/2 (b), p-38, p-p38 (c), and c-Jun, p-c-Jun (d) levels following SAH. The upper panel shows representative protein levels of JNK, p-JNK, ERK1/2, p-ERK1/2, p-38, p-p38, c-Jun and p-c-Jun. The bottom panels are quantitative data of p-JNK, p-ERK1/2, p-p38, and p-c-Jun. Tubulin was used as loading control. Data are expressed as mean ± SD (n = 6 in each group). JNK, c-jun N-terminal kinase, ERK, extracellular regulated protein kinases Definition of SAH is the same as in Fig. 2. *p < 0.05 compared with the sham group, **p < 0.01 compared with the sham group, ***p < 0.001 compared with the sham group, #p < 0.05 compared with the SAH group, ##p < 0.01 compared with the SAH group, ###p < 0.001 compared with the SAH group, NS, no statistic difference compared with the SAH group.

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