Table 3 Summary of published studies estimating ONSD using ultrasonography in healthy volunteers.

From: Ultrasonographic measurement of the optic nerve sheath diameter and its association with eyeball transverse diameter in 585 healthy volunteers

Author (Reference)

Nation

Number* [mean age (years)]

Mean ± SD (95% CI)

Range

Associated factor

Non-associated factor

Asian population

Maude11

Bangladesh

136 (NA)

4.41 (4.25–4.75) mm

4.24–4.83 mm

NA

Sex, age, HC

Shirodkar12

India

41 (27.4)

F: 4.63 ± 0.09 (4.59–4.67) mm

NA

NA

NA

M: 4.80 ± 0.10 (4.76–4.84) mm

Chen13

China

519 (46.1)

5.1 ± 0.5 (5.06–5.14) mm

3.5–6.4 mm

OND

Sex, age, weight, height, ETD

Wang14

China

230 (43.2)

3.46 ± 0.28 (3.42–3.49) mm

2.65–4.30 mm

Sex, BMI

Age, HC, waistline, MABP

Karami15

Iran

32 (59.5)

3.2 ± 0.3 (3.1–3.3) mm

2.6–4.1 mm

NA

NA

Rehman16

Pakistan

26 (34.7)

4.33 ± 0.38 (4.18–4.48) mm

NA

NA

NA

Current study

South Korea

585 (21.4)

4.11 ± 0.35 (4.09–4.14) mm

3.30–5.20 mm

ETD

Sex, weight, height, BMI, HC

Western population

Ballantyne17

UK

67 (37)

3.2–3.6 mm

2.4–4.7 mm

NA

NA

Romagnuolo18

USA

10 (NA)

Rt.: 4.6 ± 0.71 (4.09–5.11) mmLt.: 4.5 ± 0.56 (4.1–4.9) mm

NA

NA

Position

Blehar19

USA

27 (36.6)

4.3 (4.0–4.7) mm

NA

NA

NA

Shah20

USA

40

3.71–3.92 mm

NA

NA

NA

Skoloudik21

Czech Republic

16 (68.6)

3.41 mm

NA

NA

NA

Bauerle8

Germany

40 (37.1)

5.4 ± 0.6 (5.2–5.6) mm

4.3–7.6 mm

NA

Sex, age, BMI

Bauerle22

Germany

15 (24.5)

5.43 ± 0.49 (5.18–5.68) mm

4.6–6.4 mm

NA

NA

Strapazzon23

Italy

19 (39.5)

5.45 ± 0.29 (5.32–5.58) mm

4.85–5.94 mm

Hypobaric hypoxia

NA

Lochner24

Italy

21 (34.2)

Median: 5.2 (IQR: 4.8–5.5) mm

NA

NA

Sex, age

Lochner9

Italy

20 (46.3)

5.95 ± 0.68 (5.65–6.25) mm

4.5–7.7 mm

NA

NA

Amini25

USA

42 (24)

Rt.: 4.73 ± 0.73 (4.50–4.96) mm Lt.: 4.48 ± 0.62 (4.28–4.68) mm

NA

NA

NA

Lefferts26

USA

20 (24)

4.99 ± 0.68 (4.69–5.29) mm

NA

NA

Acute resistance exercise

Goeres27

Canada

120 (29.3)

3.68 ± 0.36 (2.85–4.40) mm

NA

Sex

Age, weight, height

Zeiler28

Canada

120 (29.3)

3.68 (2.85–4.40) mm

NA

NA

NA

Dinsmore29

Canada

11 (33.5)

4.2 ± 0.7 (3.8–4.6) mm

NA

End-tidal PCO2

NA

  1. *Data are number of healthy volunteers.
  2. ONSD, optic nerve sheath diameter; SD, standard deviation; CI, confidence interval; NA, not applicable; HC, head circumference; OND, optic nerve diameter; ETD, eyeball transverse diameter; BMI, body mass index; MABP, mean arterial blood pressure; IQR, interquartile range.