Table 1 Pathway enrichment analysis of significantly altered hippocampal proteins (PLS-DA, variable influence of projection (VIP)-score 1.0, significance analysis of microarrays and other omic-datasets (SAM), false-discovery rate (FDR) 0.10, and SAM q 0.10) 2 h after a single injection of a low dose of ketamine (3 mg kg−1). N = 5 mice per group and time point.
From: Ketamine’s antidepressant effect is mediated by energy metabolism and antioxidant defense system
Pathway | Number of proteins | p-value | FDR |
|---|---|---|---|
Protein processing in endoplasmic reticulum | 6 | 0,001 | 0,084 |
Purine metabolism | 6 | 0,001 | 0,084 |
Ribosome | 5 | 0,002 | 0,084 |
Fructose and mannose metabolism | 3 | 0,002 | 0,084 |
Oxidative phosphorylation (OXPHOS) | 5 | 0,002 | 0,084 |
Proteasome | 3 | 0,003 | 0,100 |
