Figure 1 | Scientific Reports

Figure 1

From: Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Figure 1

Preventive TSO treatment ameliorates DSS colitis. (A) NZW rabbits received 2500 TSO at day 1, 14 and 21 (intra-gastrically). At day 26 colitis was induced by administration of 0.1% DSS in the daily beverage for 5 days. (B) Body weight is shown as percentage of individual weight at start of DSS colitis induction (day 26). (C) Clinical symptoms (reduction in food and beverage intake, fur cleanliness, weight loss and stool consistency), were scored daily and summarized as disease activity index (DAI). Bars show mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001, two-sided p-Value, Mann-Whitney test relative to the vehicle DSS group (#) and to the vehicle water group (*). Data are pooled from two independent experiments with n = 3–4 rabbits per group.

Back to article page