Table 3 Sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio for HCC prediction using serum FGF21 in CHB patients.

From: Diverse Changes of Circulating Fibroblast Growth Factor 21 Levels in Hepatitis B Virus-Related Diseases

Cut-off of Serum FGF21 (pg/ml)

Sensitivity (%)

Specificity (%)

Youden index

Positive likelihood ratio

Negative likelihood ratio

200

100.0

74.8

1.748

3.968

0.000

225

77.8

76.5

1.543

3.311

0.290

250

66.7

80.9

1.476

3.492

0.412

275

55.6

82.6

1.382

3.195

0.538

300

55.6

84.3

1.399

3.541

0.527

325

55.6

86.1

1.417

4.000

0.516

350

55.6

89.6

1.452

5.346

0.496

375

55.6

93.0

1.486

7.943

0.477

400

44.4

93.0

1.374

6.343

0.598