Table 1 Cardiorespiratory parameters obtained during normoxia and hypoxia (F_IO₂: 0.05). The selective autonomic blockade with atropine (muscarinic blockade), sotalol (β-adrenergic blockade) and double autonomic blockade were performed under normoxic and hypoxic conditions in the Cururu toad Rhinella schneideri at 25 °C.

RR interval (s)

3.51 ± 0.26^a

2.63 ± 0.17^b

3.48 ± 0.52^a,b

2.95 ± 0.19^b

SD_RR (s)

0.29 ± 0.04^a

0.06 ± 0.01^b

0.24 ± 0.03^a

0.05 ± 0.01^b

TP_RR (ms²)

65449 ± 14793^a

3419 ± 1995^b

62107 ± 24404^a

3337 ± 1991^b

Hypoxia (F _I O ₂ :0.05) ( N  = 13)

Atropine ( N  = 6)

Sotalol ( N  = 7)

Double blockade ( N  = 13)

RR interval (s)

1.74 ± 0.13^a

1.74 ± 0.13^a,c

2.25 ± 0.23^b

2.02 ± 0.14^b,c

SD_RR (s)

0.14 ± 0.04^a

0.10 ± 0.03^a,b

0.09 ± 0.03^a,b

0.05 ± 0.01^b

TP_RR (ms²)

18849 ± 8448^a

7037 ± 4148^a,b

5977 ± 3661^a

1081 ± 431.2^b

Lung inflation cycles (events.min⁻¹)

0.93 ± 0.10

0.57 ± 0.06

1.00 ± 0.17

0.83 ± 0.17