Figure 2 | Scientific Reports

Figure 2

From: Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs

Figure 2

Peripheral blood CD4 and CD8 T-cell responses induced by VRP and WIV vaccines. PBMC were isolated at day 48 post vaccination (20 days after the booster injection) and re-stimulated in vitro with CAF or R757/10 (H1N2) virus to determine the percentage of virus-specific IFNγ (a,d), TNF (b,e) and dual cytokine (c,f) producing T cells in both the CD4 (A–C) and the CD8 (d–f) T cell subset. Asterisks indicate significant differences between two groups as calculated using unpaired one-way ANOVA followed by Tukey’s multiple comparisons test (***P < 0.0001; **P < 0.005; *P < 0.05).

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