Figure 3

Structural superposition of IDH2/R140Q_AGI-6780 (open conformation, colored yellow) and IDH2/R140Q_αKG (closed conformation, colored green) after 400 ns MD simulation.
Structural superposition of IDH2/R140Q_AGI-6780 (open conformation, colored yellow) and IDH2/R140Q_αKG (closed conformation, colored green) after 400 ns MD simulation.