Table 2 Genotype and allele frequencies of SLCO1B1 (T521C) and GSTP1 (A1578G) in cases and controls.
Gene | Genotype | Cases n(%) | Controls n(%) | OR (95%CI) | P-valuea,b |
|---|---|---|---|---|---|
SLCO1B1 | TT | 164 (36.7) | 141 (30.4) | ref | Â |
TC | 248 (55.5) | 287 (61.9) | 0.743 (0.560–0.985) | 0.023 | |
CC | 35 (7.8) | 36 (7.8) | 0.836 (0.499–1.402) | 0.291 | |
TC/CC | 283 (63.3) | 323 (69.6) | 0.753 (0.572–0.993) | 0.410 | |
T | 576 (64.4) | 569 (61.3) | ref | Â | |
C | 318 (35.6) | 359 (38.7) | 0.875 (0.723–1.058) | 0.092 | |
GSTP1 | AA | 318 (66.9) | 353 (74.3) | ref | Â |
AG | 24 (5.1) | 14 (2.9) | 1.903 (0.968–3.742) | 0.042 | |
GG | 133 (28.0) | 108 (22.7) | 1.367 (1.017–1.837) | 0.023 | |
AG/GG | 157 (33.1) | 122 (25.7) | 1.429 (1.029–1.892) | 0.008 | |
A | 660 (69.5) | 720 (75.8) | ref | Â | |
G | 290 (30.5) | 230 (24.2) | 1.375 (1.123–1.685) | 0.001 |
