Figure 1
From: Identification of shared genetic variants between schizophrenia and lung cancer
Stratified Q-Q plot for schizophrenia (SCZ) given lung cancer (LgCa). Stratified Q-Q plot of theoretical vs empirical −log10 p-values (corrected for genomic control) in schizophrenia (SCZ) below the standard GWAS threshold of -log10 p-values equal to 7.3 (equals p-values above 5 × 10−8) as a function of significance of association with lung cancer (LgCa) at the level of p < 1 (all SNPs), p < 0.1, p < 0.01, p < 0.001 respectively. Dotted lines indicate the theoretical line in case of no association. Prior to this analysis single nucleotide polymorphisms (SNPs) in the major histocompatibility complex (MHC) have been excluded.
