Figure 6 | Scientific Reports

Figure 6

From: Chitosan-Graphene Oxide 3D scaffolds as Promising Tools for Bone Regeneration in Critical-Size Mouse Calvarial Defects

Figure 6

CHT/GO 3.0 wt.% implantation stimulates early and late osteogenesis markers. (A) mRNA expression of Runx-2 at 72 h, 4 weeks, 8 weeks and 18 weeks pos-timplantation; (B) mRNA expression of OPN at 72 h, 4 weeks, 8 weeks and 18 weeks post-implantation; (C) mRNA expression of OCN at 72 h, 4 weeks, 8 weeks and 18 weeks post-implantation; (D) Immunohistochemical expression of BMP-2 and Runx-2 at 72 h and 4 weeks post-implantation; (E) Immunohistochemical expression of OPN and OCN at 8 and 18 weeks post-implantation.

Back to article page