Figure 4
C1-INH oligomers in plasma. Non-denaturing PAGE and immuno-blot analysis of plasma from patient T.M. (378 R/C) at different functional values of C1-INH. Equal plasma volumes were loaded in each line. Heat-treated plasma C1-INH (oligomer), normal human plasma (NHP) and the plasma of a patient known to have circulating oligomers (T167N)23 are shown as reference. The primary Ab used was the 12-27-15 monoclonal antibody, revealed with a secondary Ab designed for chemiluminescent detection.
