Figure 1
From: Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method
Stratified QQ (upper panel) and Enrichment (lower panel) plots. Upper Panel: Stratified QQ plots of nominal versus empirical –log10 p-values in (left) BMI as a function of significance of the association with T2D, and in (right) T2D as a function of significance of the association with BMI. Lower Panel: Fold-enrichment plots of enrichment versus nominal –log10 p-values for (left) BMI below the standard GWAS threshold of p < 5 × 10−8 as a function of significance of the association with T2D, and (right) T2D below the standard GWAS threshold of p < 5 × 10−8 as a function of significance of the association with BMI. The purple line with slope of zero represents all SNPs.
