Figure 2

Significantly altered functional connectivity maps in N171–82Q HD mice versus their littermate controls. The seed locations in different brain regions were indicated in each panel. the blue color covered regions in the HD vs WT panels indicate the brain regions which have reduced connectivity with indicated seed regions in each panel, and orange covered regions indicate the regions which have enhanced connectivity with the seed regions. n = 7 (control group) and 13 (HD group), the value is HD/control. t values were indicated by the color bars (bottom of the graph), the range is from −25 to 25 in WT or HD panels, and from −7 to 7 in HD versus HD panels. p < 0.005, corrected with Monte Carlo simulation program.