Table 1 Correlations between IL-20 expression to various clinicopathological parameters.

From: Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma

 

Number

IL-20 Exp.

P-value

Low

High

Sex

   

0.135

Male

84

39

45

 

Female

20

13

7

 

Age (years)

   

1.000

<60

48

24

24

 

60

56

28

28

 

Hepatitis

   

0.529

HBV

54

29

25

 

HCV

38

17

21

 

Both

4

1

3

 

None

8

5

3

 

Pugh-Child’s Classification

   

0.010*

A

85

45

40

 

B

6

0

6

 

C

3

0

3

 

AFP

   

0.292

<400

75

42

33

 

400

23

10

13

 

Tumor Multiplicity

   

0.003*

Solitary

61

38

23

 

Multiple

43

14

29

 

Differentiation

   

0.003*

Well/Moderately differentiated

79

46

33

 

Poorly differentiated

25

6

19

 

Primary Tumor (pT)

   

0.002*

pT1

42

27

15

 

pT2

32

18

14

 

pT3–4

30

7

23

 

AJCC Stage

   

0.002*

Stage I

40

26

14

 

Stage II

32

18

14

 

Stage III-V

32

8

24

 

CLIP score

   

0.001*

0–1

63

37

26

 

2–3

30

7

23

 

Okuda stage

   

0.003*

I

62

36

26

 

II-III

31

8

23

 
  1. HBV: viral hepatitis B.
  2. HCV: viral hepatitis C.
  3. AFP: alpha fetal protein OS: overall survival.
  4. LRFS: local recurrence free survival.
  5. CLIP: The Cancer of the Liver Italian Program.
  6. AJCC: The American Joint Committee on Cancer TNM system.