Figure 6
From: Cell-Free DNA Kinetics in a Pre-Clinical Model of Head and Neck Cancer
Plasma ctDNA levels following surgery. (a) Relative ctDNA level post-operation for rabbits having undergone surgery (n = 3 rabbits). The estimated value for the half-life of ctDNA in plasma, based on one-phase decay, is shown for each curve. (b) Correlation (Pearson r, mean ± 95% confidence interval) between ctDNA or total plasma DNA vs. tumour + lymph node volume from pre- and post-surgical removal of the tumour for only those rabbits that underwent surgery (Rabbits 6, 7 and 8). Pearson r (rp) and P values are indicated. Dashed lines represent 95% confidence interval. Asterisks indicate P < 0.05.
