Table 1 Clinical Parameters in Sjögren Syndrome Dry Eye, non-Sjögren Syndrome Dry Eye, and Normal Controls.

From: Elevation of autophagy markers in Sjögren syndrome dry eye

Characteristics

SS DE

non-SS DE

Normal control

P valuea

No. of patients (eyes)

40 (78)

24 (48)

16 (25)

 

Age (y)

53.80 ± 11.77 (28 to 78)

50.13 ± 14.80 (18 to 80)

53.43 ± 16.76 (25 to 78)

0.3602

OSDI (0–100)

47.57 ± 26.19 (2 to 100)

37.59 ± 17.94 (3.5 to 70.45)

6.77 ± 13.95 (0 to 42.5)

0.0938

Schirmer I value (mm)

2.72 ± 1.88 (0 to 8)

5.81 ± 2.21 (2 to 10)

11.46 ± 3.66 (2 to 15)

<0.0001

TBUT (s)

2.82 ± 2.30 (0 to 10)

4.63 ± 2.38 (2 to 10)

7.58 ± 1.90 (4 to 10)

<0.0001

Corneal staining score (0–6)

2.22 ± 1.47 (0 to 6)

1.73 ± 1.01 (0 to 4)

0

0.0579

Conjunctival staining score (0–6)

2.12 ± 1.34 (0 to 5)

0.77 ± 0.95 (0 to 3)

0

<0.0001

  1. SS = Sjögren Syndrome, DE = dry eye, OSDI = ocular surface disease index; TBUT = tear film break-up time; OSS = ocular surface staining.
  2. acomparison between SS DE and non-SS DE.