Table 2 Comparison of baseline and treatment for High-pressure NPPV and low-pressure NPPV.

From: High-pressure versus low-pressure home non-invasive positive pressure ventilation with built-in software in patients with stable hypercapnic COPD: a pilot study

 

High-pressure ventilation

Low-pressure ventilation

p

Baseline

3 months

Baseline

3 months

SaO2

89.08 ± 6.14

91.85 ± 6.15

91.90 ± 4.28

91.10 ± 5.04

0.43

FEV1

0.55 ± 0.11

0.62 ± 0.11

0.53 ± 0.16

0.55 ± 0.21

0.07

FVC

1.55 ± 0.64

1.70 ± 0.68

1.49 ± 0.46

1.58 ± 0.50

0.59

pH

7.37 ± 0.02

7.40 ± 0.03

7.38 ± 0.03

7.39 ± 0.03

0.26

PaCO2

58.16 ± 6.46

47.40 ± 5.23

58.85 ± 7.48

51.67 ± 7.40

0.06

PaO2

68.89 ± 15.40

73.14 ± 12.56

65.60 ± 13.99

68.42 ± 17.20

0.27

SRI

45.36 ± 11.95

54.43 ± 13.74

44.98 ± 8.82

52.95 ± 10.28

0.72

CAT

25.77 ± 3.75

21.77 ± 5.92

26.43 ± 5.06

22.24 ± 6.67

0.84

TDI

1.69 ± 1.75

−0.04 ± 2.71

0.04

  1. Values represent as means ± SD.; NPPV, non-invasive positive pressure ventilation; SaO2, arterial oxygen saturation; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PaCO2, arterial carbon dioxide pressure; PaO2, arterial oxygen pressure; SRI, Severe Respiratory Insufficiency; CAT, COPD assessment test; TDI, Transitional Dyspnoea Index.