Figure 4

Comparaison membrane proteins fully embeded compared to those having extra-membranous-domains. (a) AnisoB: T-test with Welch correction two-tailed p-value = 0.0005; mean embedded = 22.3 Å2, mean extra-membranous-domains = 27.4 Å2; M-W two-tailed p-value = 0.0003. (b) AnisoB for structures between 2.8 and 3 Å resolution: T-test two-tailed p-value > 0.99, mean = 29.44 Å2; M-W two-tailed p-value > 0.99. (c) Crystal contacts: Student’s T-test with Welch correction: two-tailed p-value < 0.0001, mean embedded = 0.089, mean extra-MB-domain = 0.057; M-W two-tailed p-value < 0.0001. (d) Resolution: Student’s T-test with Welch correction: two-tailed p-value < 0.0001, mean embedded = 2.67 Å, mean extra-MB-domain = 2.99 Å; M-W two-tailed p-value < 0.0001.