Figure 1 | Scientific Reports

Figure 1

From: Reduced cell size, chromosomal aberration and altered proliferation rates are characteristics and confounding factors in the STHdh cell model of Huntington disease

Figure 1

Cell size difference in Q111 knock-in cells. (a) Representative pictures of STHdh Q7/Q7 (STQ7) and STHdh Q111/Q111 (STQ111) cells, and (b) ImageJ-based surface area quantification of STHdh cells attached to the culture dish surface n = 3 experiments, unpaired t-tests; ***P < 0.001. (c) Representative histograms of STHdh cells and (d) quantification of the cell size of live cells in suspension, based on the relative mean forward scatter area (FSC-A); n = 4 experiments, unpaired t-tests; *P < 0.05. (e–h) Results of size determination for MEFHdh Q7/Q7 (MEFQ7) and MEFHdh Q111/Q111 (MEFQ111) cells, respectively; *P < 0.05, **P < 0.01.

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