Figure 3 | Scientific Reports

Figure 3

From: A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain

Figure 3

Histological analysis of explant-cultured mouse IVDs. Mouse IVDs were explant-cultured for three days with recombinant IL-1β (10 ng/ml) with or without T-5224 (50 μM). Paraffin-embedded sections were stained with safranin O-fast green-iron haematoxylin and subjected to immunohistochemical analysis using antibodies specific for Mmp-3, Mmp-13 and Col2. Scale bars = 100 μm.

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