Table 1 Summary of WGCNA analysis.

From: Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging

module

GO enrichment

Module hub

term.id

term.name

p.value

# genes

transcript

gene

kTotal

kWithin

black

GO:0044282

small molecule catabolic process

7.34E-19

54

uc001ffr.3

PBXIP1

1250

627

blue

GO:0099536

synaptic signaling

1.89E-17

95

uc010abi.3

NBEA

2525

900

brown

GO:0099536

synaptic signaling

5.70E-19

90

uc001bto.3

BAI2

2124

779

cyan

GO:0007005

mitochondrion organization

1.14E-33

95

uc021yem.1

NDUFA2

1434

327

darkgreen

GO:0010467

gene expression

3.22E-09

109

uc003xkt.5

ASH2L

906

67

darkred

GO:0019080

viral gene expression

2.06E-25

32

uc003hza.3

RPL34

1473

164

darkturquoise

GO:0016192

vesicle-mediated transport

3.69E-05

23

uc031pyt.1

APBB1

1180

55

green

GO:0046483

heterocycle metabolic process

4.52E-10

284

uc010wqb.2

CEP95

1766

364

greenyellow

GO:0006996

organelle organization

1.28E-08

184

uc011lhl.2

ATP6V1C1

1522

279

grey

GO:0034641

cellular nitrogen compound metabolic process

2.59E-11

482

uc003kxw.3

SOWAHA

1160

154

grey60

GO:0007399

nervous system development

5.35E-09

69

uc003nqg.3

HLA-E

586

189

lightcyan

GO:0030198

extracellular matrix organization

3.76E-16

33

uc001nsa.3

DAGLA

2339

137

lightgreen

GO:0016560

protein import into peroxisome matrix, docking

0.00963

3

uc010kgt.2

MAP7

838

150

lightyellow

GO:0043170

macromolecule metabolic process

4.66E-08

236

uc010yyo.2

DBI

1880

549

magenta

GO:0044237

cellular metabolic process

1.27E-11

467

uc009znf.2

SMUG1

1247

211

midnightblue

GO:0042455

ribonucleoside biosynthetic process

0.000362

12

uc001bbe.1

AX747516

2166

585

pink

GO:0006412

translation

3.08E-32

105

uc003ovj.2

LRRC73

1452

315

purple

GO:0034976

response to endoplasmic reticulum stress

0.0196

25

uc010sqb.2

ERBB3

1551

855

red

GO:0007272

ensheathment of neurons

2.57E-11

22

uc003bew.2

PRR5

778

108

royalblue

GO:0044763

single-organism cellular process

1.94E-06

189

uc022cbu.1

TCEAL3

1168

239

salmon

GO:0006397

mRNA processing

2.76E-28

71

uc002nxp.3

SCN1B

771

206

tan

GO:0005737

cytoplasm

6.47E-06

334

uc010jie.1

LARP1

2605

1785

turquoise

GO:0071840

cellular component organization or biogenesis

3.80E-33

856

uc002bmi.1

MRPL46

1798

470

yellow

GO:0034641

cellular nitrogen compound metabolic process

4.78E-13

399

uc001ffr.3

PBXIP1

1250

627

  1. A table showing the WGNCA modules with the most significant enrichments for GO terms, along with associated number of genes in the module that were enriched for that GO term and the associated p value for enrichment.