Figure 2 | Scientific Reports

Figure 2

From: Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease

Figure 2

Tables A–D. Fluorescent polarization structure-activity relationships of inhibitors for wild type PA organized by small molecule 2D structural type. Table A. Initial diamides. Table B. 3,5-Dichloroisonicotinyl and N-methyl derivatives. Table C. Linker heteroatom exploration. Table D. R2 optimization. The fluorescent polarization assay conditions have previously been reported17,27.

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