Table 3 Multivariate analysis1 for SR.

From: HLA-B, HLA-C and KIR improve the predictive value of IFNL3 for Hepatitis C spontaneous clearance

Factor

Condition

p

OR for SR (95% CI)

IFNL3

Non CC

0.001

1

CC

6.43 (2.10 to 19.08)

HLA-B44

Absence

0.006

1

Presence

0.18 (0.05 to 0.62)

HLA-C07

Absence

0.647

1

Presence

0.75 (0.20 to 2.59)

HLA-C12

Absence

0.029

1

Presence

0.17 (0.03 to 1.06)

KIR3DS1

Absence

0.001

1

Presence

0.09 (0.01 to 0.50)

Gender

Male

0.519

1

Female

1.50 (0.48 to 4.63)

Age

<50 years

0.929

1

≥50 years

0.94 (0.31 to 2.80)

  1. 1No interactions were found between the factors included in the model (IFNL3* HLA-B44, p = 0.999; IFNL3*HLA-C12, p = 0.998; IFNL3*KIR3DS1, p = 0.998; HLA-B44*HLA-C12, p = 0.324; HLA-B44*KIR3DS1, p = 0.999; HLA-C12*KIR3DS1, p = 0.999). Abbreviations: spontaneous resolution (SR); non-spontaneous resolution (non-SR); n (number of cases); 95% confidence interval (95% CI); odds ratio (OR).
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