Figure 6
From: Gene length as a regulator for ribosome recruitment and protein synthesis: theoretical insights
Effects of competition for resources (ribosomes) on the protein production rate. The ribosome density depends on the overall ribosome concentration c ∞. We show the ribosome density as a function of the transcript length for different concentrations of available ribosomes c ∞ (A). The curve denoted with c ∞ in the legend is built starting from the same parameters of Fig. 3A. We change c ∞ as described in the legend for the other curves. Short transcripts are less affected by changes in c ∞, as we also show in (B) where we plot the relative expression of transcripts η (defined in the text) as a function of c ∞. We used transcript with three different lengths (here L = 100, 500 and 2500). According to these results, ribosomal proteins that are short should be relatively more expressed under high ribosome competition regimes compared to other types of proteins.
