Figure 4 | Scientific Reports

Figure 4

From: High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia

Figure 4

STAP1 knockdown does not sensitize cells towards prednisolone, ibrutinib or rapamycin. (a–c) The efficacy of prednisolone (a), ibrutinib (b), and rapamycin (c) was tested in Nalm6 and Kasumi-2 cells, in which STAP1 was silenced. Three days after transduction, Nalm6 and Kasumi-2 cells were exposed to a concentration range of the indicated compounds. After four days, viability was quantified using an MTS assay. Values represent mean ± SEM of four independent experiments of Nalm6 and three independent experiments of Kasumi-2.

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