Table 1 Demographic and treatment characteristics of survivors of childhood acute lymphoblastic leukemia from the PETALE cohort.

From: Cardiometabolic Risk Factors in Childhood, Adolescent and Young Adult Survivors of Acute Lymphoblastic Leukemia – A Petale Cohort

Characteristic

Total (N = 247)

PETALE

Adults (N = 162)

Children (N = 85)

Gender, N (%)

  Male

122 (49.4)

80 (49.4)

42 (49.4)

  Female

125 (50.6)

82 (50.6)

43 (50.6)

Age at interview, years

  Mean (SD)

22.1 (6.3)

25.5 (5.1)

15.7 (1.8)

  Median (range)

21.7 (8.5–41.0)

24.7 (18.0–41.0)

16.2 (8.5–17.9)

Age at cancer diagnosis, y

  Mean (SD)

6.6 (4.6)

7.9 (5.0)

4.2 (2.2)

  Median (range)

4.7 (0.8–18.0)

6.5 (0.8–18.0)

3.6 (1.2–11.0)

Time from diagnosis, y

  Mean (SD)

15.5 (5.2)

17.7 (5.0)

11.5 (2.5)

  Median (range)

15.2 (5.4–28.2)

18.3 (6.2–28.2)

11.9 (5.4–15.6)

Risk groups, N (%)

  Standard risk

113 (45.8)

59 (36.4)

54 (63.5)

  High risk

128 (51.8)

100 (61.7)

28 (32.9)

  Very high risk

6 (2.4)

3 (1.9)

3 (3.53)

Treatment protocol, N (%)

  DFCI 87–01

24 (9.7)

24 (14.8)

0 (0.0)

  DFCI 91–01

46 (18.6)

46 (28.4)

0 (0.0)

  DFCI 95–01

73 (29.6)

56 (34.6)

17 (20.0)

  DFCI 2000–01

77 (31.2)

21 (13.0)

56 (65.9)

  DFCI 2005–01

27 (10.9)

15 (9.3)

12 (14.1)

CRT exposure, N (%)

  Total

147 (59.5)

113 (69.8)

34 (40.0)

  DFCI 87–01

18 (7.3)

18 (11.1)

0 (0.0)

  DFCI 91–01

37 (15.0)

37 (22.8)

0 (0.0)

  DFCI 95–01

45 (18.2)

34 (21.0)

11 (12.9)

  DFCI 2000–01

33 (13.4)

17 (10.5)

16 (18.8)

  DFCI 2005–01

14 (5.7)

7 (4.3)

7 (8.2)

  1. CRT, cranial radiation therapy; DFCI, Dana Farber Cancer Institute. CRT doses were ranging between 10 and 20 gray.