Figure 3
From: AICAR suppresses TNF-α-induced complement factor B in RPE cells
The inhibitory effects of AICAR on TNF-α-induced CFB expression was not affected by 5-IODO. (A) RPE cells were preincubated with 0.4 μM IODO for 1 hour and then treated with 2 mM AICAR for 1 hour followed by 10 ng/mL TNF-α for 24 hours. Western blot demonstrating the expression level of CFB in supernatants and cell lysates. (B) Densitometry of CFB in RPE cell lysate in A is shown. Representative blots are shown. *p < 0.05.
