Table 1 Gene ontology (GO) terms for changes in motor neuron mRNA expression after miR-124 overexpression.
Gene Ontology term | genes count | P-value |
|---|---|---|
Organelle envelope | 27 | 1.80E-05 |
Envelope | 27 | 1.90E-05 |
Mitochondrial part | 24 | 2.30E-04 |
Organelle inner membrane | 23 | 1.80E-07 |
Mitochondrial membrane | 22 | 1.00E-05 |
Mitochondrial envelope | 22 | 2.50E-05 |
Mitochondrial inner membrane | 21 | 1.30E-06 |
Inorganic cation transmembrane transporter activity | 16 | 8.40E-09 |
Monovalent inorganic cation transmembrane transporter activity | 14 | 4.70E-09 |
Hydrogen ion transmembrane transporter activity | 13 | 2.40E-08 |
Redox-active center | 8 | 4.60E-06 |
Cell redox homeostasis | 8 | 1.00E-04 |
Thioredoxin-like | 6 | 3.40E-04 |
Thioredoxin-like | 6 | 3.40E-04 |
Disulphide isomerase | 5 | 1.20E-06 |
Domain:Thioredoxin 2 | 5 | 9.30E-06 |
Domain:Thioredoxin 1 | 5 | 9.30E-06 |
Thioredoxin-like subdomain | 5 | 2.50E-05 |
Thioredoxin, conserved site | 5 | 7.80E-04 |
Thioredoxin domain | 5 | 9.10E-04 |
Oxidoreductase activity, acting on heme group of donors, oxygen as acceptor | 5 | 6.90E-04 |
Oxidoreductase activity, acting on heme group of donors | 5 | 6.90E-04 |
Cytochrome-c oxidase activity | 5 | 6.90E-04 |
Heme-copper terminal oxidase activity | 5 | 6.90E-04 |
PIRSF001487:protein disulfide-isomerase | 4 | 1.90E-04 |
Protein disulfide isomerase activity | 4 | 3.00E-04 |
Intramolecular oxidoreductase activity, transposing S-S bonds | 4 | 3.00E-04 |
Intramolecular oxidoreductase activity, interconverting keto- and enol-groups | 4 | 4.50E-04 |
Intramolecular oxidoreductase activity | 4 | 3.10E-02 |
Protein disulphide isomerase | 3 | 1.70E-03 |