Figure 4

Levels of glutathione (a–d) at baseline (n = 4–6) and (e–h) after 8 weeks of NAC or saline treatments (n = 6). Data are mean ± SEM. *P ≤ 0.05 vs age matched WT mice. ++ P < 0.01 vs age matched saline treated DCM mice. P values were derived from a one-way ANOVA followed by Tukey post-hoc test. Total GSH = total glutathione content, GSSG = oxidised glutathione content, GSH = reduced glutathione content, GSH:GSSG = reduced glutathione: oxidised glutathione ratio. Other abbreviations are as for Fig. 1.