Figure 4
Heat maps showing differentially expressed cytokines between all groups. Each of the four comparisons are displayed as heat maps illustrating each animal for each different cytokine. (a) ZL-M vs. ZL-F, (b) ZDF-M vs. ZDF-F, (c) ZL-M vs. ZDF-M, (d) ZL-F vs. ZDF-F. Each heat map is a graphic representation of relative expression of cardiac cytokine levels with individual cardiac samples arranged along the x-axis and cytokiness along the y-axis. Yellow indicates the highest expression for each cytokine (1.0), while dark blue indicates lower expression relative to the sample with the highest expression. Expression was normalized for each cytokine across all animals (across each row). Statistical significance was determined using Student’s t-test. p < 0.05 for all proteins, n = 5 for each group.
