Figure 6

Delicate balance between entropy and polarity in 54 analogs of 2-APB. (a) 3-d plot of the solvent accessible surface area (SASA), dipole and logP. 4 groups are distinguished by different colors. The arrow shows the direction of project after dimension reduction. (b) 2-d plot obtained from 3-d by using PCA. (c) Representative structures in each group.