Table 3 Comparison of the trapezoideal-AUC significance probabilitiesa.

From: Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria

 

N. meningitides alone

Treatment with

C6-ceramide

sphingosine

ω–C6-ceramide

AUC

215.54

154.27

2.95

5.44

Trapezoidal-area significance probabilityb,c (P value)

 

0.039792

<0.0001

<0.0001

  1. aAUC for N. meningitidis was compared across lipid treatment as a summary measure of viability over the time course. AUC was calculated from time T0h to the last sampling point (T24h). The significance probabilities are shown.
  2. bSignificance probability associated with the exact nonparametric Kruskal-Wallis test of the null hypothesis that the distribution of the trapezoidal area is the same across all treatment groups.
  3. cSignificance level 0.05.