Figure 1
Hemodynamics and extracellular histones in serum. (A) Shortening fraction (SF%) of left ventricle in sham, multiple trauma followed by damage control orthopedics (DCO) or multiple trauma followed by early total care orthopedics (ETC) at indicated time points. (B) Ejection fraction (EF%) of left ventricle in sham, multiple trauma followed by damage control orthopedics (DCO) or multiple trauma followed by early total care orthopedics (ETC) at indicated time after trauma. n = 6 pigs in each group, #DCO p < 0.05. *ETC p < 0.05. (C) Time course for extracellular histone appearance in serum from pigs after multipe trauma and DCO treatment (grey bars), ETC treatment (black bars) or sham (white bars), *differences to sham procedure were significant, p < 0.05; #differences to baseline concentrations were significant, p < 0.05. For all frames n = 6 for each bar.
