Figure 7
From: Influence of solubilization and AD-mutations on stability and structure of human presenilins
Fibrilisation assays for presenilin2 in FC14. (a) Thioflavin T binding assay: Fluorescence spectra of native and unfolded PS2 and positive control BSA with and without ThT; (b) Congo red absorption assay: Absorption spectra for native and unfolded PS2 and positive control BSA. For experimental details see Methods. See Supplementary Figure S7 for the far UV CD and absorption spectra of folded and unfolded protein.
