Figure 3
From: Discovering viral genomes in human metagenomic data by predicting unknown protein families
(a) Diagram of the bacteriophage HFM genome. This circular fragment was amplified from fecal samples using primers designed based on cluster 179a. The genome contains 7 candidate ORFs, all of which are located in the same strand and cover ~93% of the genome. Annotation suggests viral provenance due to the presence viral-like protein motifs such as a phage capsid motif (cap) and a replication protein (rep). The protein family (cluster 179a) from which the primers were designed is highlighted in light blue in ORF 6. (b) Phylogenetic tree showing the position of bacteriophage HFM in relation to 54 clearly annotated Microviridae genomes from the public databases. Due to lack of homology, it was impossible to include more distantly related sequences. It is a maximum likelihood tree, calculated using RAxML with 1000 bootstraps.
