Figure 4

Analyses of RNA-seq from TCGA dataset in 682 colon cancers and 41 NMs. (a) Expression levels of both CRCAL-3 and CRCAL-4 were significantly higher in colon cancer than in NM tissues. (b) GO term enrichment analysis confirmed the significant association of either CRCAL-3 or CRCAL-4 with cell cycle. (c) Differentially expressed lncRNAs and protein-coding genes from RNA-seq data formed a co-expression network in colon cancer tissues. Known and novel lncRNAs associated with colon cancer were identified.