Figure 3 | Scientific Reports

Figure 3

From: Promoting Induced Pluripotent Stem Cell-driven Biomineralization and Periodontal Regeneration in Rats with Maxillary-Molar Defects using Injectable BMP-6 Hydrogel

Figure 3

Characterization of BMP-6-releasing hydrogel (BMP-6-hydrogel). (A) Different osteogenic effects of the BMP-6-hydrogel group and hydrogel-only group from x-rays. (B,F) Comparison of the treatment efficacy of hydrogel with and without BMP-6 as a delivery vehicle in rat periodontal defects in parameters of percent bone volume, trabecular thickness, and trabecular number. (C) Concept of the thermosensitive hydrogel and mixed with BMP-6 10 ng/ml. (D) Transformation of BMP-6-hydrogel from hydrogel status at 4 °C to liquid status at 37 °C. (E) Biocompatibility of hydrogel to iPSCs in a crystal violet assay (upper) and lactate dehydrogenase (LDH) assay (lower), *p < 0.05, **p < 0.01.

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