Figure 8

PGE1 ameliorated renal insulin resistance via autophagy-dependent FGF21 in diabetic rats. Representative Western blot gel documents and summarized data showing the protein expression of LC3B (a), Beclin-1 (b), p62 (c), pIRS-1ser307 (d), IRS-1 (e) and FGF21 (f) in diabetic rat kidney. Representative immunohistochemistry images and summarized data of pIRS-1ser307 (g), LC3B (h) and FGF21 (i) in rat kidney. *P < 0.05 vs. Ctrl; # P < 0.05 vs. diabetic rat group (n = 3).