Table 3 Treatment Protocol and Laboratory Test of Small for Gestational Age Neonates with Necrotizing Enterocolitis Who Progressed to Stage III or Not.

From: Correlative Factors of the Deterioration of Necrotizing Enterocolitis in Small for Gestational Age Newborns

 

Stage III (n = 15)

No stage III (n = 49)

P

Albumin (n, %)

8 (53.3)

12 (24.5)

0.07

Blood transfusion (n, %)

9 (60.0)

18 (36.7)

0.11

Intravenous immunoglobulin (n, %)

2 (13.3)

5 (10.2)

0.32

Probiotics (n, %)

4 (26.7)

23 (46.9)

0.16

Anaerobic antimicrobial therapy (n, %)

11 (73.3)

31 (63.3)

0.47

Dopamine support (n, %)

5 (33.3)

13 (26.5)

0.95

Broad spectrum antibiotics use (days, mean ± SD)

11.9 ± 5.5

13.5 ± 6.9

0.42

Cessation of enteral feeding (days, mean ± SD)

7.0 ± 3.3

7.2 ± 4.8

0.89

Nasogastric suction [days, median(IQR)]

6 (1–8)

2 (0–5)

0.04

WBC count* <5 × 109/L or >20 × 109/L (n, %)

6 (40)

5 (10.2)

0.02

Platelet count* <100 × 109/L (n, %)

3 (20)

5 (10.2)

0.58

CRP* >8 mg/L (n, %)

4 (26.7)

12 (24.5)

1

Elevated CRP post NEC diagnosis, %(n)

12 (80.0)

7 (14.3)

0.0001

  1. *Baseline values were tested within 24 hours of NEC diagnosis; WBC: white blood cell; CRP: C-reactive protein; NEC: necrotizing enterocolitis; SD: standard deviation; IQR: interquartile range.
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