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Figure 1

From: Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

Figure 1

Infection of cattle with M. tuberculosis H37Rv, M. tuberculosis BTB1558 or M. bovis AF2122/97 induces similar peripheral immune responses. Blood was collected at regular intervals from cattle prior to and after experimental infection with M. tuberculosis H37Rv (n = 4), M. tuberculosis BTB1558 (n = 4), or M. bovis AF2122/97 (n = 4). Whole blood was isolated and stimulated with a cocktail of peptides derived from ESAT-6 and CFP-10. The responses in the infected cattle are shown: M. tuberculosis H37Rv (squares); M. tuberculosis BTB1558 (triangles); M. bovis AF2122/97 (circles). M. bovis infected animals were maintained for 6 weeks, M. tuberculosis groups for 10 weeks. Data for each time point is presented as the mean response + SEM.

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